The Birmingham News just reported that former researcher, H.M. Krishna Murthy, may have falsified or fabricated data. The Journal of Biological Chemistry has already retracted the paper in question, which contains PDB entry 1BEF.
If other journals follow suite the impact will be significant. According to Google Scholar, a total of 449 cite the papers in which these structures appear.
The University of Alabama at Birmingham announced that 12 structures were falsified or fabricated. The 12 questionable structures that have been deposited into the PDB are as follows: 1BEF, 1CMW, 1DF9, 2QID, 1G40, 1G44, 1L6L, 2OU1, 1RID, 1Y8E, 2A01, and 2HR0.
The publications involve a wide range of topics including: dengue viruses, serine proteases, Taq DNA polymerase, heparan sulfate proteoglycans, apolipoprotein A-II and A-I, suramin in heparin binding, and complement component 3.
The following table contains links to the structures, pdf of the journal articles and citations. The table is worth exploring if you believe you may draw conclusions based on these structures.
|PDB ID:||Journal:||Cited By:|
|1BEF||Journal of Biological Chemistry||94|
|1DF9||Journal of Molecular Biology||75|
|2QID||To be Published||0||1G44, 1G40||Cell||89||2OU1, 1L6L||Biochemistry||29||1Y8E||Biochemistry||4||1RID||PNAS||36||2A01||PNAS||95||2HR0||Nature||25|