P212121

Here it is. The ultimate list of protein crystallization resources, including websites, publications, books and databases. The purpose of this list is to provide crystallographers with useful resources related to protein crystallization. The title and author list of some resources have been shortened for ease of viewing.

Websites:
Hampton Research: Crystallization Tips (awesome) and Crystal Growth
Terese Bergfors: Protein Crystallization
Ruppweb.org: How to grow protein crystals
Emerald Biosystems: Crystallization Hits
Molecular Dimensions: Technical Tips
Davidson College: Protein Crystallization
Xtal-protocals: xtal-protocals
Enrico Stura: Crystallization Techniques -scroll down a little
Artem Evdokimov: Xtals.org (good pdf on cryo)
UCLA: Crystallization and Heavy Atom Screening
NYU: Protein Crystallization (pdf)

Publications: (first author: title)
Jancarik: Sparse matrix sampling: a screening method for crystallization of proteins
Mikol: Experimental determination of H2O equilibration rates: hanging drop method [in] crystallization
Whitesides: The origins and the future of microfluidics
Saridakis: Towards a ‘universal’ nucleant for protein crystallization
Kundrot: Which strategy for a protein crystallization project?
Carter: Quantitative Analysis: Characterization and Optimization of Protein Crystal Growth (pg. 572)
Radaev: A survey of protein-protein complex crystallizations (pg. 605)
Anand: An overview on MPD in crystallization and in crystals of biological macromolecules (pdf)
Cudney: Screening and Optimization Strategies for Macromolecular Crystal Growth (pg. 414)
Wooh: Comparison of three commercial sparse-matrix crystallization screens
Pusey: Life in the fast lane for protein crystallization and X-ray crystallography (pdf)
Chayen: Turning protein crystallisation from an art into a science
Hassell: Crystallization of protein-ligand complexes (pdf)
Chayen: Protein crystallization: from purified protein to diffraction-quality crystal
Hasek: Poly(ethylene glycol) interactions with proteins
Bonnete: Interest of the normalized second virial coefficient and interaction potentials for crystallizing large macromolecules (pdf)
Cannone: Crystallization of bFGF-DNA aptamer complexes using a Sparse Matrix designed for protein–nucleic acid complexes (pdf)
D’Arcy: Practical aspects of using the microbatch method in screening conditions for protein crystallization
Izaac: Assessment of a preliminary solubility screen to improve crystallization trials: uncoupling crystal condition searches

Books:
Alexand Mcpherson: Crystallization of Biological Macromolecules (the classic)
Terese Bergfors: Protein Crystallization, Second Edition (IUL Biotechnology Series)
Sylvie Doublie: Preparation and Crystallization of Macromolecules
Larry DeLucas: Membrane Protein Crystallization
Carola Hunte, et al.: Membrane Protein Purification and Crystallization
Naomi E. Chayen : Protein crystallization strategies for structural genomics

Databases:
Biological Macromolecule Crystallization Database (post)
Cryoprotectant Database for Protein Crystals (post)
Marseille Protein Crystallization Database (post)
Surface Entropy Reduction prediction
Membrane Protein DataBank

Tools:
Paul Hubbard: The Crystal Screen Wizard (post)
Hari Jayaram: Gridzilla

Mentioned on P212121.com:
Emerald Biosystems: Crystal card and Plugmaker
Mycrolytic: Crystal Former and SmartScreen

Know of any other helpful resources? Then please feel free to share in the comment section!
Thanks!

Related Posts:

• Extracting Structural Information from the Protein Structure Initiative
• CoFactor: The organic enzyme cofactor database
• Loops at the Protein Geometry Database
• Protein-DNA Interface Database: PDIdb
• PDB Atlas: JenaLib

6 Awesome Insights so far | Have Your Say!

1. 

   Mary Canady
   September 22nd, 2009 at 10:05 AM #

   Hi Sean–what about listing all of the synchrotrons?

   Mary

2. 

   Paul
   September 22nd, 2009 at 12:41 PM #

   Hi Mary. I have a fairly extensive list of synchrotrons in a Google Maps mashup (feel free to add any that are not listed):

   http://www.pageforaday.com/xtalwizard/maps/

   Web Administrator, if you want to make a list, feel free to use the above web page as a data source.

   Paul

3. 

   Sean
   September 22nd, 2009 at 7:55 PM #

   Hey Paul, thanks for sharing resource! Oh and there is no web admin, just me.

   Sean

4. 

   Hari Jayaram
   October 6th, 2009 at 8:37 PM #

   Hi Sean,
   I wrote this python library and a graphical tool that helps you easily calculate pipetting volumes and grid-layouts for crystal optimization using 24, 96 and 384 wells called gridzilla . Would be thrilled if you can add a link to the tools section of your site .

5. 

   Sean
   October 9th, 2009 at 9:12 AM #

   Hello Hari – welcome!

   I stopped by your site and checked out your tool, nice work. I will have to download it and check out the features. I really love that you put a tutorial video with the program, thanks.

6. 

   Kevin
   October 24th, 2009 at 9:42 PM #

   Good job. Thanks mate!