Kissing Waters
Jul 5, 2009
Kissing waters: two blobs of electron density that are linked.
Ideally, the kissing waters will end up being your ligand of interest.
Posted by Sean |
Categories: Crystallographic Data Processing, Crystallographic Data Refinement, Uncategorized | Tagged: Electron Denstiy, Kissing Waters, Macromolecular Crystallography |
Hobosic
July 6th, 2009 at 11:15 PM #
Hi,
Can i take a one small pic from your blog?
NO?
July 7th, 2009 at 10:59 AM #
closer and your ligand would be hydrogen peroxide or NO?
Sean
July 7th, 2009 at 11:25 AM #
Thanks for asking. I sent you an email.
Paul
July 9th, 2009 at 9:39 PM #
Madonna circa 1992 springs to mind! On a side-note, what’s your personal hydrogen bonding distance cut-off? On a related side-note, I wonder how many PDBs contain “low barrier” hydrogen bonds? I assume it’s inversely related to resolution.
Sean
July 10th, 2009 at 11:02 AM #
@NO? This is an example using two waters
@Paul Haha! Cut-off as in too far away (depends on the environment and atoms involved), but as a general rule would have a hard time justifying anything more than 3.5 Angstroms